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Updated: Aug 18, 2026

Ferric Chloride-induced Murine Thrombosis Models
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セレクティブ・トロンビン阻害による血小板豊富な動脈栓塞の予防

I K Jang1, H K Gold, A A Ziskind

  • 1Cardiac Unit, Massachusetts General Hospital, Boston 02114.

Circulation
|January 1, 1990
PubMed
まとめ

ヘパリンはウサギの動脈栓塞に対して無効でしたが,合成トロンビン阻害剤であるアグラトロバンは凝固形成を大幅に防ぐことができました. これは,選択的トロンビン阻害が動脈閉塞を予防するための有望なアプローチであることを示唆しています.

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