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Updated: Apr 1, 2026

Native Polyacrylamide Gel Electrophoresis Immunoblot Analysis of Endogenous IRF5 Dimerization
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FOXO3-IRF7遺伝子の調節回路は,抗ウイルス反応の炎症的な続きを制限する

Vladimir Litvak1, Alexander V Ratushny, Aaron E Lampano

  • 1Seattle Biomedical Research Institute, Seattle, Washington 98109, USA.

Nature
|September 18, 2012
PubMed
まとめ

FOXO3は,IRF7の転写を制御することによって,抗ウイルス反応の負の調節剤として作用します. この発見は,免疫防衛のバランスと過剰な炎症の予防に不可欠な新しい調節回路を明らかにしています.

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