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関連する概念動画

Ligand-Gated Ion Channel Receptor: Gating Mechanism01:30

Ligand-Gated Ion Channel Receptor: Gating Mechanism

Ligand-gated ion channels are transmembrane proteins that play a vital role in intercellular communication and functions of the nervous system. They allow the influx of ions across the membrane once the neurotransmitter binds, allowing the subsequent transmission of electrical excitation across the neurons. Other ligand-gated ion channels, like the γ-aminobutyric acid (GABA) receptor, permit anions like chloride into the cells on the binding of the GABA molecule. Their entry into the cell...
Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
Mechanically-gated Ion Channels01:12

Mechanically-gated Ion Channels

Mechanically-gated ion channels are proteins found in eukaryotic and prokaryotic cell membranes that open in response to mechanical stress. Tension, compression, swelling, and shear stress can alter the conformation of the protein, opening a transmembrane channel that allows the passage of ions for signal transmission. In eukaryotes, mechanically-gated channels are distributed in several regions like the neurons, lungs, skin, bladder, and heart, where they play critical roles in numerous...
Non-gated Ion Channels01:24

Non-gated Ion Channels

Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism.
Non-gated Ion Channels01:24

Non-gated Ion Channels

Ion channels are specialized proteins on the plasma membrane that allow charged ions to pass down their electrochemical gradient. Their main function is to maintain the membrane potential which is critical for cell viability. These channels are either gated or non-gated and can transport more than a thousand ions within milliseconds for the cellular event to occur.
Compared to the gated ion channels, the non-gated channels, also known as leakage or passive channels, have no gating mechanism.
Ligand-gated Ion Channels01:19

Ligand-gated Ion Channels

Ligand-gated ion channels are transmembrane proteins with a channel for ions to pass through and a binding site for a ligand. The channel opens only when a ligand attaches to the binding site.
Three Subfamilies of Ligand-gated Ion Channels
Ligand-gated ion channels fall into three subfamilies. The 'Cys-loop' includes the nicotinic acetylcholine receptors, γ-aminobutyric acid (GABA), glycine, and 5-hydroxytryptamine receptors. The second one is the 'Pore-loop' channels that include the...

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関連する実験動画

Updated: May 18, 2026

Electric-field Control of Electronic States in WS2 Nanodevices by Electrolyte Gating
10:36

Electric-field Control of Electronic States in WS2 Nanodevices by Electrolyte Gating

Published on: April 12, 2018

イオン性液体における単一分子電気化学ゲーティング

Nicola J Kay1, Simon J Higgins, Jan O Jeppesen

  • 1Department of Chemistry, Donnan and Robert Robinson Laboratories, University of Liverpool, Liverpool L69 7ZD, UK.

Journal of the American Chemical Society
|September 19, 2012
PubMed
まとめ
この要約は機械生成です。

研究者は,リドックス活性型ピロロテトラチアフルバレン (pTTF) ブリッジを使用して,イオン液体内の分子伝導性を研究しました. 彼らはユニークな"オフオンオフオンオフ"伝導電位スイッチングを観察し,電荷転送プロセスに関する洞察を明らかにしました.

さらに関連する動画

Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers
09:54

Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers

Published on: November 19, 2015

Characterizing Electron Transport through Living Biofilms
08:52

Characterizing Electron Transport through Living Biofilms

Published on: June 1, 2018

関連する実験動画

Last Updated: May 18, 2026

Electric-field Control of Electronic States in WS2 Nanodevices by Electrolyte Gating
10:36

Electric-field Control of Electronic States in WS2 Nanodevices by Electrolyte Gating

Published on: April 12, 2018

Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers
09:54

Multifunctional, Micropipette-based Method for Incorporation And Stimulation of Bacterial Mechanosensitive Ion Channels in Droplet Interface Bilayers

Published on: November 19, 2015

Characterizing Electron Transport through Living Biofilms
08:52

Characterizing Electron Transport through Living Biofilms

Published on: June 1, 2018

科学分野:

  • 分子電子は分子電子である.
  • 電気化学 電気化学について
  • マテリアルサイエンス 材料科学

背景:

  • 単分子電子は,電荷輸送の正確な制御を提供します.
  • レドックス活性分子は,電子状態を通して導電性を調節することができます.
  • イオン性液は,分子特性を研究するためのユニークな環境を提供します.

研究 の 目的:

  • イオン性液中のリドックス活性分子ブリッジの単分子導電性を調査する.
  • 分子トランジスタにおける酸化還元状態の電気化学的ゲート化を調査する.
  • 充電移転のダイナミクスと再構成エネルギーの特徴を明らかにする.

主な方法:

  • スキャニングトンネル顕微鏡 (STM) による電気化学単分子トランジスタ構成 ブレイクジャンクション.
  • 媒介として室温イオン液体 (RTIL) を利用する.
  • リドックス状態を制御するために,in situ電化学ポテンシャルスイーピングを行います.

主要な成果:

  • 観察された"オフオンオフオンオフ"伝導電流のスイッチング行動は,pTTFのリドックス変異と相関しています.
  • RTILでモノケーション状態とディケーション状態の両方を成功裏に研究しました.
  • 連続した2段階の電荷移転プロセスとして導電性をモデル化します.
  • RTILでの推定再構成エネルギーは ~1.2 eVで,水溶液 (~0.4 eV) よりも大幅に高い.

結論:

  • RTIL環境は,以前アクセス不可能な状態を含む,酸化還元活性分子に関する詳細な研究を促進します.
  • 外界圏の再構成エネルギーは,イオン性液体における分子結合の間の電荷移転に重要な役割を果たします.
  • 観測されたスイッチング行動は,分子電子スイッチのモデルを提供します.