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トリプトファンのスイッチは,光活性化プラチナ抗がん複合体のためのスイッチです

Jennifer S Butler1, Julie A Woods, Nicola J Farrer

  • 1Department of Chemistry, University of Warwick, Coventry CV4 7AL, UK.

Journal of the American Chemical Society
|September 21, 2012
PubMed
まとめ

プラチナ (((IV) 複合体トランス,トランス,トランス-[Pt (((N3) 2 (((OH) 2 (((py) 2) 1) は,青い光の照射で強力な癌細胞毒性を示しています. この効果は,アジジル基形成を抑制するl-トリプトファンによって切断されます.

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