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Drug Toxicity: Risk factors

Drug Toxicity: Risk factors

Adverse Drug Reactions (ADRs) are potential complications that arise during pharmacotherapy, influenced by multiple risk factors. Age plays a significant role; both neonates and the elderly are at heightened risk due to their respective immature and diminished metabolic and elimination processes. Gender also impacts ADRs, with females experiencing a 1.5 to 1.7-fold greater risk than males, which may be linked to pharmacokinetic, pharmacodynamic, and hormonal differences. Notably, neonates, the...

Acute Coronary Syndrome IV: Interprofessional Care

Acute Coronary Syndrome IV: Interprofessional Care

IntroductionThe management of Acute Coronary Syndrome (ACS) aims to minimize myocardial damage, preserve myocardial function, and prevent complications.Initial ManagementInpatient management involves continuous cardiac monitoring, preferably in an ICU, focusing on blood pressure, serum sodium, potassium, and creatinine levels, and urine output. Ongoing pharmacologic management is crucial for stabilizing the patient.Supplemental Oxygen: Administer supplemental oxygen if oxygen saturation is...

Self-Discrepancy Theory

Self-Discrepancy Theory

One influential perspective on what motivates people's behavior is detailed in Tory Higgin's self-discrepancy theory (Higgins, 1987). He proposed that people hold disagreeing internal representations of themselves that lead to different emotional states.

Self-Presentation: Self-Monitoring and Self-Handicapping

Self-Presentation: Self-Monitoring and Self-Handicapping

People can go to great lengths to protect their self-image and present themselves in ways that they want others to see them. Sociologist Erving Goffman presented the idea that a person is like an actor on a stage. Calling his theory dramaturgy, Goffman believed that we use “impression management” to present ourselves to others as we hope to be perceived. Each situation is a new scene, and individuals perform different roles depending on who is present (Goffman, 1959). Think about the way you...

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Updated: May 18, 2026

Pre-clinical Model of Cardiac Donation after Circulatory Death

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

自傷行為による早死:多センターコホート研究.

Helen Bergen¹, Keith Hawton, Keith Waters

¹University of Oxford Centre for Suicide Research, Department of Psychiatry, Warneford Hospital, Headington, Oxford, UK.

Lancet (London, England)

|September 22, 2012

まとめ

自傷行為をする人は,特に自然死による早死のリスクが著しく高く,社会経済的欠乏に関連した死亡率が増加しています. これは,自己傷害患者の管理において,身体的健康を重視する必要性を強調しています.

科学分野:

公衆衛生は公衆衛生である.
エピデミオロジーエピデミオロジー
クリニカル・メディシン臨床医学

背景:

自傷行為は,早死のリスクの増加と関連しています.
特定の原因による死亡率とその自己傷害患者の社会経済的要因との関連を理解することは極めて重要です.

研究の目的:

自傷行為をする個人の原因特異的な早死を調査する.
この集団における社会経済的貧困と死亡率の関連性を調べる.

主な方法:

イギリスの救急治療室に自傷を呈した患者についてコホート研究が行われた (2000年~2007年).
社会経済的地位は,多重貧困指数にリンクされた郵便番号を使用して評価されました.
2009年まで死亡率データを収集し,年齢標準化死亡率 (SMRs) と失命年数 (YLL) を分析した.

主要な成果:

この研究では,30,950人が参加し,6.1%が追跡中に死亡しました.
死亡率は,自己傷害患者 (SMR 3.6) で,特に男性において,一般の人々と比較して,著しく高かった.
自然原因による死亡は予想より2.5~7.5倍多く,循環器系および消化器系疾患が主な原因となっている.
あらゆる死因と自然死因による死亡率は,社会経済的貧困のレベルが高くなるにつれて著しく増加した.

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Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

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Pre-clinical Model of Cardiac Donation after Circulatory Death

Pre-clinical Model of Cardiac Donation after Circulatory Death

Published on: August 2, 2019

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Comprehensive Autopsy Program for Individuals with Multiple Sclerosis

Published on: July 19, 2019

結論:

身体的健康と平均寿命は,自傷行為をする個人に著しく低下します.
自傷害の臨床管理は,心理的社会問題と並行して,身体的健康ニーズの評価を統合する必要があります.