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Updated: May 18, 2026

Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy
12:03

Evaluation of the Efficacy And Toxicity of RNAs Targeting HIV-1 Production for Use in Gene or Drug Therapy

Published on: September 5, 2016

ヒト schlafen 11によるHIVタンパク質合成のコドン使用ベースの阻害

Manqing Li1, Elaine Kao, Xia Gao

  • 1Section of Molecular Biology, Division of Biological Sciences, University of California San Diego, La Jolla, California 92093, USA.

Nature
|September 25, 2012
PubMed
まとめ

人間のSLFN11タンパク質は,ウイルスのタンパク質合成を選択的に阻害することによって,ヒト免疫不全ウイルス1 (HIV-1) の産生を抑制します. コドンバイアスを認識することで,後期的なウイルス産生を標的とし,新しい先天性免疫抗ウイルス戦略を提供します.

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