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Updated: May 18, 2026

Microfluidic Mixers for Studying Protein Folding
12:42

Microfluidic Mixers for Studying Protein Folding

Published on: April 10, 2012

非常に適合性の高いタンパク質のネイティブ状態で,自発的な機械的な展開経路のような機械的な展開経路があります

Pétur O Heidarsson1, Immanuel Valpapuram, Carlo Camilloni

  • 1Structural Biology and NMR Laboratory, Department of Biology, University of Copenhagen, Ole Maaløes Vej 5, 2200 Copenhagen N, Denmark.

Journal of the American Chemical Society
|September 26, 2012
PubMed
まとめ

アシル-コア結合タンパク質 (ACBP) は驚くべき機械的柔軟性を示し,緊張下で自発的な変性化のように展開します. このネイティブに折りたたまれたタンパク質は,中間状態よりも大きな変形性を示し,タンパク質力学の以前のモデルに挑戦しています.

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