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Updated: May 18, 2026

CRISPR-Mediated Reorganization of Chromatin Loop Structure
09:20

CRISPR-Mediated Reorganization of Chromatin Loop Structure

Published on: September 14, 2018

遺伝子ループは,転写方向性を強化する

Sue Mei Tan-Wong1, Judith B Zaugg, Jurgi Camblong

  • 1Sir William Dunn School of Pathology, University of Oxford, South Parks Road, Oxford OX1 3RE, UK.

Science (New York, N.Y.)
|September 29, 2012
PubMed
まとめ

積極的に転写されたmRNA遺伝子によって形成される遺伝子ループは,ノンコーディングRNA (ncRNA) の合成を制限する. Ssu72タンパク質または遺伝子ループの無活性化により,異なったncRNAの生成が増加し,転写方向性を強制します.

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