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Updated: May 18, 2026

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凝固因子Xは,ヒト種Cアデノウイルスに対する先天的な免疫を活性化させます

Konstantin Doronin1, Justin W Flatt, Nelson C Di Paolo

  • 1Department of Medicine, University of Washington, Seattle, WA 98195, USA.

Science (New York, N.Y.)
|September 29, 2012
PubMed
まとめ

ヒトアデノウイルスは凝固因子X (FX) を使用して,Toll型受容体4 (TLR4) 信号伝達を介して先天的免疫を誘発します. この相互作用をブロックすると,免疫遺伝子の活性化が妨げられ,新しいウイルス-宿主免疫機構が明らかになる.

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