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Updated: May 18, 2026

Combined Immunofluorescence and DNA FISH on 3D-preserved Interphase Nuclei to Study Changes in 3D Nuclear Organization
13:55

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Published on: February 3, 2013

免疫グロブリン-κ再配列のクローンアレルによる事前決定

Marganit Farago1, Chaggai Rosenbluh, Maya Tevlin

  • 1Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel-Canada, Hebrew University Medical School, POB 12272, Ein Kerem, Jerusalem 91120, Israel.

Nature
|October 2, 2012
PubMed
まとめ

幹細胞は遺伝子発現の柔軟性を維持しますが,初期の免疫細胞は1つの遺伝子コピーのみを使用することを約束します. この安定したクローン選択は,免疫グロブリン・カッパの位置における非同期的な複製タイミングによって事前に決定される.

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