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Updated: May 18, 2026

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor
07:16

Monitoring Hippo Signaling Pathway Activity Using a Luciferase-based Large Tumor Suppressor (LATS) Biosensor

Published on: September 13, 2018

ミトコンドリアの欠陥は,ドロソフィラのヒッポシグナル伝達を通して,非自律的な腫瘍進行を誘導する

Shizue Ohsawa1, Yoshitaka Sato, Masato Enomoto

  • 1Division of Genetics, Kobe University Graduate School of Medicine, 7-5-1 Kusunoki-cho, Chuo-ku, Kobe 650-0017, Japan.

Nature
|October 2, 2012
PubMed
まとめ

ミトコンドリア機能障害と腫瘍性Rasは,腫瘍の進行を推進するために協力します. これには,活性酸素種,c-Junアミノ端末キナーゼ (JNK) 信号伝達,およびヒッポの経路が関与し,転移を促進します.

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A Protocol for Genetic Induction and Visualization of Benign and Invasive Tumors in Cephalic Complexes of Drosophila melanogaster07:23

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