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関連する概念動画

Vision01:24

Vision

Vision is the result of light being detected and transduced into neural signals by the retina of the eye. This information is then further analyzed and interpreted by the brain. First, light enters the front of the eye and is focused by the cornea and lens onto the retina—a thin sheet of neural tissue lining the back of the eye. Because of refraction through the convex lens of the eye, images are projected onto the retina upside-down and reversed.
The Retina01:32

The Retina

The retina is a layer of nervous tissue at the back of the eye that transduces light into neural signals. This process, called phototransduction, is carried out by rod and cone photoreceptor cells in the back of the retina.
Anatomy of the Eyeball01:20

Anatomy of the Eyeball

The eye is a spherical, hollow structure composed of three tissue layers. The outer layer — the fibrous tunic, comprises the sclera — a white structure — and the cornea, which is transparent. The sclera encompasses some of the ocular surface, most of which is not visible. However, the 'white of the eye' is distinctively visible in humans compared to other species. The cornea, a clear covering at the front of the eye, enables light penetration. The eye's middle layer, the vascular tunic,...
Photoreceptors and Visual Pathways01:22

Photoreceptors and Visual Pathways

At the molecular level, visual signals trigger transformations in photopigment molecules, resulting in changes in the photoreceptor cell's membrane potential. The photon's energy level is denoted by its wavelength, with each specific wavelength of visible light associated with a distinct color. The spectral range of visible light, classified as electromagnetic radiation, spans from 380 to 720 nm. Electromagnetic radiation wavelengths exceeding 720 nm fall under the infrared category, whereas...
Visual System01:26

Visual System

Light enters the eye through the cornea, a transparent, dome-shaped surface covering the surface of the eyeball that helps to direct and focus incoming light. This light is then channeled toward the pupil, an adjustable opening whose size is controlled by the iris. The iris, a pigmented muscle, regulates the amount of light entering the eye by contracting or dilating the pupil, thereby ensuring optimal light levels for clear vision.
Once through the pupil, the light passes through the lens, a...

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関連する実験動画

Updated: May 17, 2026

Whole-mount Retinal Organoid Visualization with Cellular Resolution
09:20

Whole-mount Retinal Organoid Visualization with Cellular Resolution

Published on: June 20, 2025

網膜の波は,発達中の視覚系全体でパターン化された活動を調整する.

James B Ackman1, Timothy J Burbridge, Michael C Crair

  • 1Department of Neurobiology, Yale University School of Medicine, New Haven, Connecticut 06510, USA.

Nature
|October 13, 2012
PubMed
まとめ
この要約は機械生成です。

コリン神経伝達によって誘発される自発的な網膜波は,目を開ける前に新生児マウスの視覚系を通して伝播する. このパターンの活動は,視力の発生前に視覚回路の発達を導きます.

さらに関連する動画

Live-imaging of the Drosophila Pupal Eye
09:54

Live-imaging of the Drosophila Pupal Eye

Published on: January 12, 2015

関連する実験動画

Last Updated: May 17, 2026

Whole-mount Retinal Organoid Visualization with Cellular Resolution
09:20

Whole-mount Retinal Organoid Visualization with Cellular Resolution

Published on: June 20, 2025

Live-imaging of the Drosophila Pupal Eye
09:54

Live-imaging of the Drosophila Pupal Eye

Published on: January 12, 2015

科学分野:

  • 神経科学は神経科学である.
  • 発達生物学 発達生物学について
  • 視覚システム開発 視覚システム開発

背景:

  • 神経系の発達は遺伝的要因と神経細胞の活動に依存している.
  • 活動依存的発達は感覚経験より先行し,自発的な活動に役割があることを示唆する.
  • 産前 in vivo 神経活動の起源と特徴は,ほとんど未知のままである.

研究 の 目的:

  • 目を開ける前に発達中の視覚系における自発的な神経活動の存在と性質を調査する.
  • この初期の活動の起源,伝播パターン,および神経伝達物質への依存を決定する.
  • この活動の下流の視覚処理領域への影響を評価する.

主な方法:

  • 生きた新生児マウスで光学画像技術を用いた.
  • 網膜と視覚経路全体で観察された自発的な活動パターン.
  • アクティビティ生成におけるコレリン神経伝送の役割を調査した.

主要な成果:

  • 目を開ける前に全視系に広がる,自己発現した網膜活動の波が記録されている.
  • 双眼網膜における偏好的なイニシエーションを特定し,半球間の空間時間的な相関関係を示した.
  • 網膜波が中脳と第一視野皮質の活動の主な原動力であることを発見しました.

結論:

  • 網膜の自発的な活動は,視覚系の発達における主要な産前駆動因子である.
  • このパターンの活動には,半球内および半球間回路の構造化に不可欠な情報が含まれています.
  • コリネルジックシグナル伝達は,視覚の前にこれらの発達信号を生成するために不可欠です.