人間のRNAメチルトランスフェラーゼBCDIN3Dは,マイクロRNAの処理を調節する

Blerta Xhemalce1, Samuel C Robson, Tony Kouzarides

  • 1Wellcome Trust/Cancer Research UK Gurdon Institute, The Henry Wellcome Building of Cancer and Developmental Biology, University of Cambridge, Tennis Court Road, Cambridge CB2 1QN, UK.

Cell
|October 16, 2012
PubMed
まとめ

新しいRNAメチルトランスフェラーゼ,BCDIN3DがO-メチラートマイクロRNA (miRNA) 前駆体で発見され,その成熟を阻害しました. この発見は,がん細胞の成長に影響を与える新しいmiRNAメチル化経路を明らかにしています.

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