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Updated: May 7, 2026

MicroRNA-based Regulation of Picornavirus Tropism
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複数の腫瘍抑制剤を無効化するウイルスポリマーの組み立てと機能の構造的基礎である

Horng D Ou1, Witek Kwiatkowski, Thomas J Deerinck

  • 1Molecular and Cell Biology Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|October 16, 2012
PubMed
まとめ

アデノウイルスオンコプロテインE4-ORF3は,二重体を組み立てることで核ポリマーを形成します. このウイルスのタンパク質マトリックスは,複数の腫瘍抑制剤を捕まえて,腫瘍生成のための新しいメカニズムを明らかにします.

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