トランスコロナリー・ケミカル・アブレーション (トランスコロナリー・ケミカル・アブレーション)
P Brugada1, H de Swart, J Smeets
1Department of Cardiology, University of Limburg, Maastricht, The Netherlands.
Circulation
|March 1, 1990
まとめ
この研究では,心房動脈 (AV) の節動脈にエタノールを注射することで,心房動脈節を効果的に破壊し,心房動患者における心房率を制御することが示されています. 一般的には安全ですが,冠動脈閉塞による心臓発作を患った患者がいました.
科学分野:
- 心臓病学 心臓病学
- 介入性心臓病学 介入性心臓病学
- 電気生理学 電気生理学
背景:
- 症状のある心房細動は,しばしば制御不能な心室動脈率を示します.
- 現在の治療法は,耐火性の症例の管理に限界がある可能性があります.
研究 の 目的:
- AV結節動脈経由でエタノール注射を使用して,心房 (AV) 節の選択的化学アブレーションの有効性と安全性を評価する.
- 治療目的でAV結節動脈をキャセテライズする可能性を評価する.
主な方法:
- 症状のある心房細動を患った7人の患者で,AV結節動脈の選択的 катетеризация.
- 暫定的なAVブロック後の96%エタノールの0.5-2mlの投与は,冷凍塩水で誘発されました.
- AV伝導の変化と心臓酵素濃度のモニタリング.
主要な成果:
- 完全な心房静脈 (AV) ブロックは5人の患者で達成されました.
- さらに2人の患者で,心室速度の症状制御が観察されました.
- 6人の患者で最小限の酵素上昇が発生し,1人の患者は冠動脈閉塞による心筋梗塞を発症した.
結論:
- AV結節動脈の選択性カテーテル化は,現在の血管新生術技術で達成可能である.
- AV節のエタノールアブレーションは,心房動における心房率を制御するための有効な方法である.
- 心筋梗塞などの重篤な合併症の可能性は,慎重に患者の選択と手順のモニタリングを必要とします.
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