オブストラクティブ・ハイパートロフィック・カルジオミオパシーによるアルコールのセプトアブレーション後の生存率
Paul Sorajja1, Steve R Ommen, David R Holmes
1Division of Cardiovascular Diseases and Internal Medicine, Mayo Clinic, 200 1st Street SW, Rochester, MN 55905, USA. paul.sorajja@mayo.edu
Circulation
|October 19, 2012
まとめ
阻害性高縮性心筋病変 (HCM) のアルコール隔膜切除後の長期的な生存率は好ましい. 生存率は,一般の人々と外科的な心筋切除手術と比較し,突然の心臓死のリスクが増加していない.
科学分野:
- 心臓病学 心臓病学
- 介入性心臓病学 介入性心臓病学
- ハイパルトロフィック心筋症の研究
背景:
- アルコールセプトアブレーションは,阻害性多動性心筋病 (HCM) の治療法です.
- この手順の後の長期的な結果と生存率は,さらなる調査を必要とします.
研究 の 目的:
- 阻害性HCMのためにアルコールのセプトアブレーションを受けた患者の長期的な生存を評価する.
- 生存率を一般の人々と比較し,外科手術による骨髄切除術を行う.
主な方法:
- 第3次性HCMリファールセンターでセプトアブラションを受けた177人の患者の遡及的分析.
- 追跡期間は5.7年でした.
- 生存データと,年齢と性別を合わせた一般人口と外科手術による切除コホートとの比較.
主要な成果:
- 全死亡率のない生存率は,一般人口の生存期望に似ていた.
- 生存率は,隔離された外科手術によるミエクトミーを受けた年齢と性別が一致した患者 (8年評価:79%対79%) と比較可能でした.
- 残留左心室流出管のグラデーションは,アブレーション後の独立して,よりよい長期的な生存を予測した.
結論:
- 経験豊富なオペレータによる慎重に選択された患者のアルコールのセプトアブレーションは,長期的な生存率を好意的に提供します.
- 生存率は,一般の人々や外科手術による切除術と比較できます.
- この処置は,突然の心臓死のリスクを増大させるようには見えない.
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