高リスクの心血管疾患を有する集団における心肺運動検査の安全性について
Joseph Skalski1, Thomas G Allison, Todd D Miller
1Division of Cardiovascular Diseases and Department of Internal Medicine, Mayo Clinic, 200 First Street SW, Rochester, MN 55905, USA.
Circulation
|October 24, 2012
まとめ
心肺運動テスト (CPX) は,高リスクの心臓病患者にとって安全です. この研究では,さまざまな高リスクの心血管疾患の集団において,CPX中に0.16%の低い有害事象発生率が見つかりました.
科学分野:
- 心臓病学 心臓病学
- 運動生理学 運動生理学
- クリニカル診断士
背景:
- 心肺運動テスト (CPX) は,心血管疾患における機能障害の評価のために,ピーク酸素摂取量 (Vo2) を測定します.
- CPXの既存の安全性データは,主に冠動脈疾患および心不全の患者からのものです.
- CPXの安全性に関するデータは,より広範な,高リスクの心臓病集団において限られている.
研究 の 目的:
- 心肺運動テスト (CPX) の安全性を調査する.
- 様々な高リスクの心臓診断を持つ異質なコホートでCPXの安全性を評価する.
- これらの患者におけるCPX中の有害事象の発生率を決定する.
主な方法:
- 4250人の患者で5060件のCPX研究を遡及的にレビューした.
- 様々な高リスクの心疾患 (例えば,心不全,心筋縮性心筋症,肺高血圧,大動脈狭窄症) を有する患者を含む.
- ストレステスト中に発生した主要な有害事象の分析.
主要な成果:
- CPX中に合計8件の有害事象が発生し,0.16%の低い有害事象発生率をもたらしました.
- 最も頻繁に発生した有害事象は,持続した心室低心率 (6例) であった.
- CPX手順では死亡事故は記録されていません.
結論:
- 心肺運動テスト (CPX) は,高い安全性プロファイルを示しています.
- CPXは,複雑で高リスクの心血管疾患を持つ患者にとっても安全な手順です.
- 発見は,さまざまな心臓病患者のグループでCPXの臨床使用を拡大することを支持しています.
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