血圧に関する栄養素全体の関連研究です
Ioanna Tzoulaki1, Chirag J Patel, Tomonori Okamura
1Department of Hygiene and Epidemiology, University of Ioannina School of Medicine, Ioannina, Greece.
Circulation
|October 25, 2012
まとめ
この研究では,フォラシンやリボフラビンなどのB族ビタミンが,血圧 (BP) と逆に関連していることが判明しました. これらの発見は,食事と心血管の健康を理解するために,栄養素全体のアプローチの重要性を強調しています.
科学分野:
- 栄養科学とは,栄養科学である.
- 心血管の健康について
- エピデミオロジー エピデミオロジー
背景:
- 栄養素と血圧 (BP) の関連性を理解することは,公衆衛生にとって極めて重要です.
- これらの関係を検証するには,包括的で,偏らない,栄養素全体にわたるアプローチが必要である.
研究 の 目的:
- 様々な栄養素とBPとの関連性を体系的に評価・検証する.
- 摂食および補充栄養素の摂取がシストリックおよびダイアストリックBPに与える影響を調査する.
主な方法:
- 国際マクロ/微量栄養素と血圧の研究 (INTERMAP) に参加した4680人のデータを活用した.
- 複数の線形回帰分析を用いて,トレーニングとテストセットに分層した.
- 4つの米国国立健康と栄養検査調査 (NHANES) のコホートを使用して,外部から検証された結果.
主要な成果:
- アルコール,ナトリウムとカリウムの比率,シストリックBPとの間の直接的な関連性を特定しました.
- 摂食中のリン,マグネシウム,鉄,チアミン,フォラシン,リボフラビンとシストリックBPとの間には逆の関連性が見つかりました.
- ダイエット用フォラシンとリボフラビンとダイアストリックBPとの逆関連が確認され,効果サイズは0.97mmHgまでで,シストリックBPの減少です.
結論:
- ビタミンB (フォラシン,リボフラビン,チアミン) とBP.の間で,重大な逆相関が確認されました.
- この研究は,栄養素とBPの関連性を体系的かつ公正に評価しています.
- ビタミンBと血圧の調節の間のこれまで十分に調査されていない関係を強調します.
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