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Hydrogen Bonds01:04

Hydrogen Bonds

A hydrogen bond is formed when a weakly positive hydrogen atom already bonded to one electronegative atom (for example, the oxygen in the water molecule) is attracted to another electronegative atom from another polar molecule, such as water (H2O), hydrogen fluoride (HF), or ammonia (NH3). The huge electronegativity difference between the H atom (2.1) and the atom to which it is bonded (4.0 for an F atom, 3.5 for an O atom, or 3.0 for an N atom), combined with the very small size of an H atom...
Hydrogen Bonds00:26

Hydrogen Bonds

Hydrogen bonds are weak attractions between atoms that have formed other chemical bonds. One of these atoms is electronegative, like oxygen, and has a partial negative charge. The other is a hydrogen atom that has bonded with another electronegative atom and has a partial positive charge.
Hydrogen Bonds Control the World!
Because hydrogen has very weak electronegativity when it binds with a strongly electronegative atom, such as oxygen or nitrogen, electrons in the bond are unequally shared.
Valence Bond Theory02:45

Valence Bond Theory

Overview of Valence Bond Theory
Valence Bond Theory02:42

Valence Bond Theory

Coordination compounds and complexes exhibit different colors, geometries, and magnetic behavior, depending on the metal atom/ion and ligands from which they are composed. In an attempt to explain the bonding and structure of coordination complexes, Linus Pauling proposed the valence bond theory, or VBT, using the concepts of hybridization and the overlapping of the atomic orbitals. According to VBT, the central metal atom or ion (Lewis acid) hybridizes to provide empty orbitals of suitable...
Covalent Bonding and Lewis Structures02:46

Covalent Bonding and Lewis Structures

Compared to ionic bonds, which results from the transfer of electrons between metallic and nonmetallic atoms, covalent bonds result from the mutual attraction of atoms for a “shared” pair of electrons.
Intermolecular Forces03:13

Intermolecular Forces

Atoms and molecules interact through bonds (or forces): intramolecular and intermolecular. The forces are electrostatic as they arise from interactions (attractive or repulsive) between charged species (permanent, partial, or temporary charges) and exist with varying strengths between ions, polar, nonpolar, and neutral molecules. The different types of intermolecular forces are ion–dipole, dipole–dipole, hydrogen bonds, and dispersion; among these, dipole–dipole, hydrogen bonds, and dispersion...

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Updated: May 17, 2026

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
06:44

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

ハロゲン結合は,分子容器の内部で発生する.

Hamdy S El-Sheshtawy1, Bassem S Bassil, Khaleel I Assaf

  • 1School of Engineering and Science, Jacobs University Bremen, Campus Ring 1, D 28759 Bremen, Germany.

Journal of the American Chemical Society
|November 10, 2012
PubMed
まとめ
この要約は機械生成です。

クキュルビット[6]ウリルマクロサイクルは,2つのユニークなハロゲン結合を通して二酸化物素を結合する. 1つは水を含み,もう1つはカルボニルπ系との垂直相互作用であり,タンパク質-リガンド相互作用の洞察を提供します.

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Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
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Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

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Solvent Bonding for Fabrication of PMMA and COP Microfluidic Devices

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関連する実験動画

Last Updated: May 17, 2026

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding
06:44

From Molecules to Materials: Engineering New Ionic Liquid Crystals Through Halogen Bonding

Published on: March 24, 2018

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers
08:51

Coulomb Explosion Imaging as a Tool to Distinguish Between Stereoisomers

Published on: August 18, 2017

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Published on: January 17, 2017

科学分野:

  • 超分子化学 超分子化学
  • 化学結晶学 化学結晶学とは
  • コンピューティング・ケミストリー

背景:

  • Cucurbit[6]urilは,宿主-ゲスト複合体を形成することが知られている合成マクロサイクルです.
  • ハロゲン結合は,分子認識と結晶工学において極めて重要な非共性相互作用である.
  • 様々な化学環境におけるハロゲン結合の理解は,新しい材料や薬物の設計に不可欠です.

研究 の 目的:

  • キュキュルビット[6]ウリルと分子ジブロミン (Br2) とダイオジン (I2) の間に形成される宿主-ゲストインクルージョン複合体を調査する.
  • これらの複合体の安定化に関与するハロゲン結合相互作用の性質と幾何学を解明する.
  • これらの相互作用を生物学的システムで観察されたものと比較し,それらの基礎となる電子的要因を探求する.

主な方法:

  • 挿入複合体の正確な構造を決定するために,X線結晶学を用いた.
  • 既存の小分子結晶構造の統計分析が行われました.
  • 量子化学計算 (MP2/aug-cc-pVDZ-PP) は,モデルのシステムとして尿素を用いて行われました.

主要な成果:

  • クキュルビット[6]ウリルは,Br2とI2でインクルージョン複合体を形成し,ダイハロゲンは傾斜軸幾何学を採用する.
  • 2つの異なるハロゲン結合がダイハロゲンを安定させる:水との従来のO·X結合と,カーボニルπ系との垂直O·X結合.
  • 垂直のハロゲン結合は,非線形的な歪み (約. 140° O··X-X 角度),タンパク質-リガンド相互作用に似ています.

結論:

  • この研究は,ダイハロゲンとキュキュルビットのカルボニル基のπ系[6]uril.の間の真の垂直ハロゲン結合の形成を確認している.
  • これらの垂直の相互作用は,従来のハロゲン結合,特にカルボニル基の電子提供代用物質と競合する.
  • この発見は,合成および生物学的コンテキストの両方で,ハロゲン結合に関する貴重な洞察を提供し,特にタンパク質のハロゲン化リガンドに関連しています.