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Updated: May 17, 2026

Vasodilation of Isolated Vessels and the Isolation of the Extracellular Matrix of Tight-skin Mice
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インタールイウキンの受容体はMYD88-ARNO-ARF6カスケードを活性化し,血管の安定性を破壊する

Weiquan Zhu1, Nyall R London, Christopher C Gibson

  • 1Department of Medicine, University of Utah, Salt Lake City, Utah 84112, USA.

Nature
|November 13, 2012
PubMed
まとめ

インタールイウキン-1βは,NF-κBから独立して,新しいMYD88-ARNO-ARF6経路を通じて,内皮の障壁機能を破壊する. この経路をSecinH3で阻害すると,血管の安定性と炎症性疾患のアウトカムが改善されます.

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