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Updated: May 17, 2026

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells
09:04

Activation and Measurement of NLRP3 Inflammasome Activity Using IL-1β in Human Monocyte-derived Dendritic Cells

Published on: May 22, 2014

カルシウムセンサー受容体は,Ca2+とcAMPを通じてNLRP3炎症体を調節する

Geun-Shik Lee1, Naeha Subramanian, Andrew I Kim

  • 1Inflammatory Disease Section, Medical Genetics Branch, National Human Genome Research Institute, National Institutes of Health, Bethesda, Maryland 20892, USA.

Nature
|November 13, 2012
PubMed
まとめ

カルシウム感知受容体 (CASR) は,カルシウム (Ca2+) と周期性AMP (cAMP) 信号伝達を介してNLRP3炎症体を活性化します. CASR機能障害は,CAPSのような自己炎症性疾患に寄与する.

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