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Updated: May 10, 2026

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets
08:08

Increasing Pulmonary Artery Pulsatile Flow Improves Hypoxic Pulmonary Hypertension in Piglets

Published on: May 11, 2015

肺高血圧における新たな治療戦略として,エンドプラズマ網膜のストレスを軽減する

Peter Dromparis1, Roxane Paulin, Trevor H Stenson

  • 1Department of Medicine Cardiology, University of Alberta, Edmonton, AB, Canada T6G 2B7.

Circulation
|November 15, 2012
PubMed
まとめ

4-フェニルブチラート (PBA) のような化学チャペロンは,エンドプラズマ網膜 (ER) のストレスを軽減することによって,肺動脈高血圧を治療することができます. この新しいアプローチは,肺動脈機能を改善し,疾患の進行を逆転させるため,ERストレスをターゲットにしています.

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