サルモネラは,マノース-6-リン酸受容体とリソソーム機能の逆行密輸を抑制する

Kieran McGourty1, Teresa L Thurston, Sophie A Matthews

  • 1Section of Microbiology, Centre for Molecular Microbiology and Infection, Imperial College London, Armstrong Road, London SW7 2AZ, UK.

Science (New York, N.Y.)
|November 20, 2012
PubMed
まとめ

サルモネラ・エンテリカは,エフェクターSifAを使用して,マノース-6-リン酸受容体 (MPR) の密輸を妨害することによって,宿主細胞リゾソーム機能を妨害します. この細菌戦略は,ライソソームの活性性を低下させることでサルモネラ菌の増殖を促進します.

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