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Updated: May 16, 2026

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones
10:17

Efficient Construction of Drug-like Bispirocyclic Scaffolds Via Organocatalytic Cycloadditions of α-Imino γ-Lactones and Alkylidene Pyrazolones

Published on: February 7, 2019

部分脱硫/減少戦略による高度サイクルされたランチビオティックペニシジンAの構造的特徴化

Christopher T Lohans1, Zedu Huang, Marco J van Belkum

  • 1Department of Chemistry, University of Alberta, Edmonton, Alberta, Canada T6G 2G2.

Journal of the American Chemical Society
|November 22, 2012
PubMed
まとめ

研究者らは,ペニシジンAを発見し,ペニバチルスポリミキサからの新しいランチバイオティクスを発見しました. この高度にサイクルされた抗微生物ペプチドは,6つのチオエーテルクロスリンクを備えており,食品保存と治療のための可能性を秘めています.

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