111 左心室血栓の血小板イメージングにおいて. システミックエンボリアの予測値
1Department of Medicine, Seattle Veterans Administration Medical Center, Washington 98108.
Circulation
|April 1, 1990
まとめ
左心室血栓を示す陽性なインジウム111血小板画像は,進行中の血栓活性を示唆しています. この発見は,ネガティブな画像と比較して,全身栓塞のリスクの増加を著しく予測しています.
科学分野:
- 心臓病学 心臓病学
- 核医学は,核医学である.
- トロンボシス研究研究
背景:
- 左心室血栓 (LVT) 形成は,心筋梗塞の合併症である.
- 血栓形成活動の評価は,栓塞リスクの予測に極めて重要です.
研究 の 目的:
- LVTのための陽性インジウム111 (111In) 血小板画像が全身栓塞を予測するかどうかを評価する.
- 血栓率を比較するために,陽性および陰性111In患者の血小板画像.
主な方法:
- 血小板画像で111Inが陽性だった34人の患者と,陰性画像で69人の患者の遡及的比較.
- 血栓イベントを評価するために,追跡期間は平均38ヶ月でした.
- 年齢,心臓発作歴,エジェクション分数,治療法など,患者の特徴を分析した.
主要な成果:
- 血液栓塞は,画像が陽性であった患者の21%で,画像が陰性であった患者の3%で発生した (p=0.002).
- 精算分析によると,ポジティブなイメージを持つ患者の86%が42ヶ月で栓塞のない状態であったが,ネガティブなイメージを持つ患者の98% (p<0.01) はそうであった.
結論:
- 陽性111LVTの血小板画像は,全身栓塞の有意な予測因子である.
- このイメージング方式は,エンボリックイベントのリスクが高い患者を特定することができます.
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