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Updated: May 16, 2026

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors
12:40

A Method for Screening and Validation of Resistant Mutations Against Kinase Inhibitors

Published on: December 7, 2014

SRC-ファミリーの不可逆的なキナーゼ阻害剤によって,異なる活性部位核性体を選択的に標的にする

Nathan N Gushwa1, Sumin Kang, Jing Chen

  • 1Howard Hughes Medical Institute, Department of Cellular and Molecular Pharmacology, University of California, San Francisco, San Francisco, California 94158, United States.

Journal of the American Chemical Society
|November 30, 2012
PubMed
まとめ

新しい化学探査機は,生体細胞のSrcファミリーキナーゼを正確に標的にしています. これらのツールは,薬剤の選択性を理解し,ポナチニブのような治療によってどのキナーゼが影響を受けるかを特定するのに役立ちます.

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Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays13:22

Kinase Inhibitor Screening In Self-assembled Human Protein Microarrays

Published on: October 23, 2019

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