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Updated: May 16, 2026

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture
09:37

Combining Non-reducing SDS-PAGE Analysis and Chemical Crosslinking to Detect Multimeric Complexes Stabilized by Disulfide Linkages in Mammalian Cells in Culture

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タンパク質に共通する二硫化物ブリッジの驚くべき固有光安定性

Anne B Stephansen1, Rasmus Y Brogaard, Thomas S Kuhlman

  • 1Department of Chemistry, University of Copenhagen, Universitetsparken 5, DK-2100 Copenhagen Ø, Denmark.

Journal of the American Chemical Society
|December 6, 2012
PubMed
まとめ

光化学的安定性は,天然の分子にとって極めて重要です. ディスルファイド結合 (S-S) は,振動し,エネルギーを変換することで生き残り,構造的な特徴が根本分離を制限している場合でも,再構成できるようにします.

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