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Updated: May 16, 2026

Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine
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Preparation of Enantiopure Non-Activated Aziridines and Synthesis of Biemamide B, D, and epiallo-Isomuscarine

Published on: June 13, 2022

イボレノリドAは,Khaya ivorensisからの前例のない免疫抑制マクロリドである:構造的解明とバイオインスピレーションによる総合成

Bo Zhang1, Yao Wang, Sheng-Ping Yang

  • 1State Key Laboratory of Drug Research, Shanghai Institute of Materia Medica, Chinese Academy of Sciences, 555 Zuchongzhi Road, Shanghai 201203, P. R. China.

Journal of the American Chemical Society
|December 11, 2012
PubMed
まとめ

Khaya ivorensisからの新しいマクロリドであるイボレノリドAが合成され,特徴づけられました. この化合物とそのエナチオメルは,強力な選択的な免疫抑制作用を示し,潜在的な治療用途を提供しました.

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