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Updated: May 16, 2026

Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates
14:32

Deacetylation Assays to Unravel the Interplay between Sirtuins (SIRT2) and Specific Protein-substrates

Published on: February 27, 2016

ヒストン脱酸化酵素SIRT6は,がん代謝を制御する腫瘍抑制剤です

Carlos Sebastián1, Bernadette M M Zwaans, Dafne M Silberman

  • 1The Massachusetts General Hospital Cancer Center, Harvard Medical School, Boston, MA 02114, USA.

Cell
|December 11, 2012
PubMed
まとめ

SIRT6は,がん細胞の代謝を調節することによって,腫瘍抑制剤として作用します. SIRT6の喪失は腫瘍の成長と攻撃性を促進し,癌の発達と進行における重要な役割を強調しています.

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