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Updated: Feb 24, 2026

In Situ Monitoring of Transiently Formed Molecular Chaperone Assemblies in Bacteria, Yeast, and Human Cells
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In Situ Monitoring of Transiently Formed Molecular Chaperone Assemblies in Bacteria, Yeast, and Human Cells

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領域間のエネルギー的な牽引戦が,Hsp70分子チャペロンのアロステリック活性状態を生み出します

Anastasia Zhuravleva1, Eugenia M Clerico, Lila M Gierasch

  • 1Department of Biochemistry and Molecular Biology, University of Massachusetts, Amherst, MA 01003, USA.

Cell
|December 11, 2012
PubMed
まとめ

熱ショックタンパク質70 (Hsp70) 分子チャペロンは,タンパク質の結合と機能を調節するためにアロステリーを使用します. 研究者は,E. coli DnaKのアロステリック活性状態を特定し,信号伝送のための重要な相互作用を明らかにしました.

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