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Updated: May 16, 2026

Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and Recombination
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Preparation of Meiotic Chromosome Spreads from Mouse Oocytes for Assessment of Synapsis and Recombination

Published on: July 18, 2025

ハエのMCM複合体の進化は,BLMヘリケースを阻害することによって,メオティッククロスオーバーを促進します

Kathryn P Kohl1, Corbin D Jones, Jeff Sekelsky

  • 1Curriculum in Genetics and Molecular Biology, University of North Carolina, Chapel Hill, NC 27599, USA.

Science (New York, N.Y.)
|December 11, 2012
PubMed
まとめ

ハエでは,ミニクロモソーム維持 (MCM) タンパク質がMsh4-Msh5複合体を置き換えて,メオティッククロスオーバーの生成を保証しました. このMCM複合体は,クロスオーバーを容易にするために進化し,Msh4-Msh5.5の損失を克服しました.

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Frequency and Distribution of Crossovers in Caenorhabditis elegans Meiosis by SNP Genotyping using Real-time PCR06:18

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Checkpoints throughout the cell cycle serve as safeguards and gatekeepers, allowing the cell cycle to progress in favorable conditions and slow or halt it in problematic ones. This regulation is known as the cell cycle control system.
Cyclin-dependent kinases, or Cdks, work in concert with cyclins to control cell cycle transitions. M-Cdk, a complex of Cdk1 bound to M cyclin, is a well-known example of this coordinated control that drives the transition from the G2 to the M phase.
M cyclin...
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