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Updated: May 16, 2026

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase
11:01

Preparation and In Vivo Use of an Activity-based Probe for N-acylethanolamine Acid Amidase

Published on: November 23, 2016

非ステロイド性抗炎症薬の結合部位が脂肪酸アミドヒドロラーゼに結合している

Laura Bertolacci1, Elisa Romeo, Marina Veronesi

  • 1Drug Discovery and Development, Istituto Italiano di Tecnologia, Via Morego 30, 16163 Genoa, Italy.

Journal of the American Chemical Society
|December 18, 2012
PubMed
まとめ

非ステロイド性抗炎症薬 (NSAIDs) は,エンドカンナビノイドを分解する酵素である脂肪酸アミドヒドロラーゼ (FAAH) をブロックすることができます. この二重作用は,NSAIDとエンドカンナビノイド経路の効果を組み合わせることで,改善された疼痛緩和につながる可能性があります.

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