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Updated: May 16, 2026

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer
09:08

Integration of Bioinformatics Approaches and Experimental Validations to Understand the Role of Notch Signaling in Ovarian Cancer

Published on: January 12, 2020

モザイク型PPM1D変異は,乳がんや卵巣がんの傾向と関連しています

Elise Ruark1, Katie Snape, Peter Humburg

  • 1Division of Genetics & Epidemiology, The Institute of Cancer Research, Sutton SM2 5NG, UK.

Nature
|December 18, 2012
PubMed
まとめ

PPM1D遺伝子の希少なタンパク質切断変異は,乳がんや卵巣がんのリスクの増加と関連しています. これらのモザイク変異は,機能の獲得効果を引き起こす可能性があり,がんの傾向と管理戦略に影響を与えます.

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