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Updated: May 15, 2026

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs
10:32

Combined Use of Tail Vein Metastasis Assays and Real-Time In Vivo Imaging to Quantify Breast Cancer Metastatic Colonization and Burden in the Lungs

Published on: December 19, 2019

β-カテニン駆動がんは,生存と腫瘍発生のためにYAP1転写複合体を必要とします

Joseph Rosenbluh1, Deepak Nijhawan, Andrew G Cox

  • 1Department of Medical Oncology, Dana-Farber Cancer Institute, 450 Brookline Avenue, Boston, MA 02215, USA.

Cell
|December 19, 2012
PubMed
まとめ

発がん性β-カタニン (β-カタニン) は,YAP1とTBX5.5との複合体を形成することで癌を誘発する. YES1キナーゼを阻害すると,この複合体は破壊され,β-カタニン依存性がんの成長を止めます.

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Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter11:32

Identification of Transcription Factor Regulators using Medium-Throughput Screening of Arrayed Libraries and a Dual-Luciferase-Based Reporter

Published on: March 27, 2020

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System09:55

All-optical Mechanobiology Interrogation of Yes-associated Protein in Human Cancer and Normal Cells using a Multi-functional System

Published on: December 20, 2021

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