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Updated: May 15, 2026

Establishment of a High-throughput Setup for Screening Small Molecules That Modulate c-di-GMP Signaling in Pseudomonas aeruginosa
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サイクルGMP-AMPは,細胞塩基DNAによる先天性免疫シグナル伝達における内生的な第2伝達物質である

Jiaxi Wu1, Lijun Sun1,2, Xiang Chen1

  • 1Department of Molecular Biology University of Texas Southwestern Medical Center Dallas, TX 75390-9148.

Science (New York, N.Y.)
|December 22, 2012
PubMed
まとめ

細胞塩基DNAは新しいシグナル伝達経路を誘発する. この経路はサイクルGMP-AMP (cGAMP) を生成し,STINGを活性化し,抗菌防御のためのインターフェロン生産につながります.

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