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Updated: May 15, 2026

Presynapse Formation Assay Using Presynapse Organizer Beads and “Neuron Ball” Culture
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神経伝達物質の放出におけるMunc18とMunc13の重要な機能の再構成

Cong Ma1, Lijing Su, Alpay B Seven

  • 1Key Laboratory of Molecular Biophysics, Ministry of Education, and Institute of Biophysics and Biochemistry, Huazhong University of Science and Technology, Wuhan 430074, China. cong.ma7@gmail.com

Science (New York, N.Y.)
|December 22, 2012
PubMed
まとめ

神経伝達物質の放出には,Munc18-1やMunc13のような特定のタンパク質が必要です. この研究は,シンタキシン-1-SNAP-25ヘテロダイマーではなく,シンタキシン-1-Munc18-1複合体が融合を開始し,Munc18-1とMunc13がプロセスをオーケストラしていることを示しています.

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