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Updated: May 15, 2026

Revealing the Ferroptotic Phenotype of Medulloblastoma
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哺乳類のフラタキシン (frataxin) は,de novo Fe4S4クラスター・アセンブリの際に硫黄の生成と鉄の侵入を制御する

Florent Colin1, Alain Martelli, Martin Clémancey

  • 1Translational Medicine and Neurogenetics, Institut de Génétique et de Biologie Moléculaire et Cellulaire, Illkirch, France.

Journal of the American Chemical Society
|December 26, 2012
PubMed
まとめ

フラタキシン (FXN) は,鉄硫黄クラスター組立機械を安定させ,鉄の侵入を制御し,効率的な[Fe4S4]クラスター転送を可能にします. これは,フリードリヒに関する洞察を明らかにします.

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