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Updated: May 15, 2026

Purification of Human S100A12 and Its Ion-induced Oligomers for Immune Cell Stimulation
12:55

Purification of Human S100A12 and Its Ion-induced Oligomers for Immune Cell Stimulation

Published on: September 29, 2019

人間のカルプロテクチンによる高親和性マンガンの調整は,カルシウムに依存しており,ダイマー界面で形成されるヒスティジンに富んだ部位を必要とします

Joshua A Hayden1, Megan Brunjes Brophy, Lisa S Cunden

  • 1Department of Chemistry, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139, USA.

Journal of the American Chemical Society
|January 2, 2013
PubMed
まとめ

カルプロテクチン (CP) は,カルシウムで強化された特定のHis (His) (4) 部位でマンガン (Mn (II)) を隔離します. このタンパク質は金属をケラートし,微生物の増殖を抑制し,特にカルシウムグラデーションに反応する.

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