戦略的リドックスリレーは,生物活性カルデノリドであるオアバゲニンのスケーラブルな合成を可能にする

関連する実験動画

Updated: May 15, 2026

Solid-phase Synthesis of [4.4] Spirocyclic Oximes
05:15

Solid-phase Synthesis of [4.4] Spirocyclic Oximes

Published on: February 6, 2019

Hans Renata1, Qianghui Zhou, Phil S Baran

  • 1Department of Chemistry, The Scripps Research Institute, La Jolla, CA 92037, USA.

Science (New York, N.Y.)
|January 5, 2013
PubMed
まとめ

研究者は,心不全薬の主要な前駆体であるオアバゲニンへのスケーラブルなステロイド半合成経路を開発しました. この方法は,治療の可能性が向上した新しいカルデノリド類の効率的な生産と探査を可能にします.

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Redox Reactions

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