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スマートG-クアドルプレックスリガンドのモデル

Romain Haudecoeur1, Loic Stefan, Franck Denat

  • 1Institut de Chimie Moléculaire de l' Université de Bourgogne, CNRS UMR6302, 9, Avenue Alain Savary, 21000 Dijon, France.

Journal of the American Chemical Society
|January 10, 2013
PubMed
まとめ

研究者らは,G-四重複DNAに結合すると構造が変化するが,二重複DNAには結合しないスマートなG-四重複DNAリガンドを開発した. このイノベーションは,G-四重複のDNA構造の高い選択性を保証します.

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