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Updated: May 15, 2026

Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis
07:26

Quantitative PCR-based Assay to Measure Sonic Hedgehog Signaling in Cellular Model of Ciliogenesis

Published on: January 31, 2025

シリアのGタンパク質結合受容体Gpr161は,cAMPシグナル伝達を通じてSonic hedgehog経路を否定的に調節する

Saikat Mukhopadhyay1, Xiaohui Wen, Navneet Ratti

  • 1Department of Research Oncology, Genentech Inc., South San Francisco, CA 94080, USA. saikat.mukhopadhyay@utsouthwestern.edu

Cell
|January 22, 2013
PubMed
まとめ

G-タンパク質結合受容体Gpr161は,プライマリシリアにおけるソニック・ヘッジホッグ (Shh) 信号調節に不可欠である. その喪失により,SHH信号伝達が増加し,神経管の発達に影響を与えます.

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