関連する実験動画

Updated: May 15, 2026

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE
12:43

Monitoring Activation of the Antiviral Pattern Recognition Receptors RIG-I And PKR By Limited Protease Digestion and Native PAGE

Published on: July 29, 2014

ヒトIFITタンパク質によるウイルス5'-PPP-RNA認識の構造的基礎

Yazan M Abbas1, Andreas Pichlmair, Maria W Górna

  • 1Department of Biochemistry, Groupe de Recherche Axé sur la Structure des Protéines, McGill University, Montreal, Quebec H3G 0B1, Canada.

Nature
|January 22, 2013
PubMed
まとめ

テトラトリコペプチドリピート (IFIT) のインターフェロン誘発タンパク質は,5'-トリフォスファート群 (PPP-RNA) のウイルスRNAを直接認識する. この構造的な洞察は,IFITが先天的な抗ウイルス防御に不可欠なウイルスRNAを区別する方法を明らかにします.

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