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Updated: May 14, 2026

Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method
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Isotopic Effect in Double Proton Transfer Process of Porphycene Investigated by Enhanced QM/MM Method

Published on: July 19, 2019

重酵素の運動同位体効果は,アラニンレースマースにおける陽子の移動に起因する

Michael D Toney1, Joan Nieto Castro, Trevor A Addington

  • 1Department of Chemistry, University of California-Davis, One Shields Avenue, Davis, California 95616, USA. mdtoney@ucdavis.edu

Journal of the American Chemical Society
|February 5, 2013
PubMed
まとめ

アラニンラセメーズ酵素の重度のペルデュテレーションは,タンパク質の振動運動が,触媒作用中の陽子の移転に不可欠であることを明らかにする. この発見は,酵素機構と反応動態の理解に影響を与えます.

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