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Updated: May 14, 2026

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer
06:51

Utilizing 18F-FDG PET/CT Imaging and Quantitative Histology to Measure Dynamic Changes in the Glucose Metabolism in Mouse Models of Lung Cancer

Published on: July 21, 2018

腫瘍発生におけるPKCζによる栄養ストレス誘発の代謝再プログラム制御

Li Ma1, Yongzhen Tao, Angeles Duran

  • 1Sanford-Burnham Medical Research Institute, 10901 N. Torrey Pines Road, La Jolla, CA 92037, USA.

Cell
|February 5, 2013
PubMed
まとめ

タンパク質キナーゼCゼタ (PKCζ) 欠乏症により,がん細胞は,セリン生物合成経路経由でグルタミンを使用し,代謝を適応させることができます. PKCζの損失は腫瘍の成長を促進し,代謝性腫瘍抑制剤としての役割を示している.

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