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Updated: May 12, 2026

Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal
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Oct4GiP Reporter Assay to Study Genes that Regulate Mouse Embryonic Stem Cell Maintenance and Self-renewal

Published on: May 30, 2012

多能性の確立におけるTET1とTET2のNANOG依存機能

Yael Costa1, Junjun Ding, Thorold W Theunissen

  • 1Wellcome Trust-Medical Research Council Cambridge Stem Cell Institute, University of Cambridge, Tennis Court Road, Cambridge CB2 1QR, UK.

Nature
|February 12, 2013
PubMed
まとめ

研究者らは,体細胞の再プログラミングの強化に不可欠なTET1とTET2を含む新しいNANOG関連タンパク質を発見しました. これらのタンパク質は,NANOGと物理的に相互作用し,触媒活動を通じて多能性の確立を促進します.

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