妊娠中の高血圧と,その後の慢性疾患のリスク
Tuija Männistö1, Pauline Mendola, Marja Vääräsmäki
1Division of Epidemiology, Statistics and Prevention Research, Epidemiology Branch, Eunice Kennedy Shriver National Institute of Child, Health and Human Development, National Institutes of Health, Rockville, MD 20852, USA. mannistoTI@mail.nih.gov
Circulation
|February 13, 2013
まとめ
妊娠中の高血圧は,妊娠中の高血圧を含む,心臓血管疾患,腎臓疾患,糖尿病の長期的なリスクを大幅に増加させます. 早期のモニタリングと介入は,影響を受けた女性にとって極めて重要です.
科学分野:
- 心血管伝染病学 心血管伝染病学
- 生殖器保健は,生殖器の健康についてです.
- 公衆衛生は公衆衛生である.
背景:
- 妊産前出血症は,将来の心血管疾患の既知の危険因子です.
- 妊娠に関連した高血圧の他の形態に関連した心血管リスクに関するデータは限られている.
研究 の 目的:
- 妊娠中の様々なタイプの高血圧に伴う心臓血管疾患,腎臓疾患,糖尿病の長期的なリスクを調査する.
主な方法:
- 北フィンランド出生コホート1966 (N=10,314人) のデータを使用した.
- 妊娠中の血圧に関する将来的なデータを,産前記録とアンケートから収集した.
- フィンランドのレジストリを通じて確認された後の診断は,平均39.4年の追跡期間で確認された.
- 高血圧と正常血圧の女性のリスクを比較するために,雇用された調整された危険比率 (HRs).
主要な成果:
- 妊娠中の高血圧は,タイプに関係なく,その後の心血管疾患と高血圧のリスクの増加と関連していました.
- 妊娠期高血圧は,不全性心臓病,心筋梗塞,心不全,不全性脳卒中,腎臓病,糖尿病のリスクを高めました.
- 孤立したシストリックおよびダイアストリック高血圧の特定のリスクは,心筋梗塞による死亡および心不全性疾患を含む特定されました.
結論:
- 妊娠中の高血圧は,心臓血管疾患,慢性腎臓疾患,糖尿病の将来の高いリスクの強い指標です.
- これらのリスクは,既知の危険因子がない場合でも存在します.
- 妊娠に関連した高血圧の女性には,臨床モニタリング,危険因子評価,および適切な介入が推奨されます.
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