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Updated: May 14, 2026

4D Imaging of Protein Aggregation in Live Cells
08:59

4D Imaging of Protein Aggregation in Live Cells

Published on: April 5, 2013

混雑した細胞環境では,タンパク質とタンパク質の相互作用により,本来の状態の安定性が低下する

Ryuhei Harada1, Naoya Tochio, Takanori Kigawa

  • 1RIKEN Advanced Institute for Computational Science, 7-1-26 minatojima-minamimachi, Chuo-ku, Kobe, Hyogo 650-0047 Japan.

Journal of the American Chemical Society
|February 14, 2013
PubMed
まとめ

細胞の混雑は,直接的な相互作用によってタンパク質を不安定化させ,それがコンパクトな構造のみを好むという考えに異議を唱えます. この研究は,混雑した環境下でのタンパク質の安定性の重要な要因として,タンパク質-タンパク質相互作用を明らかにしています.

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