人類史前時代の足跡をたどったマウス
Samuel H Vohr1, Richard E Green
1Department of Biomolecular Engineering, University of California, Santa Cruz, Santa Cruz, CA 95064, USA.
Cell
|February 19, 2013
まとめ
エクトディスプラシンA受容体 (EDAR) のV370A変種は,ヒトに強い選択性を示しています. この研究は,その起源を明らかにし,マウスを用いて,その変異体の現象的効果を詳細に説明しています.
科学分野:
- 人間の進化遺伝学
- 分子生物学は分子生物学である.
- 発達生物学 発達生物学とは
背景:
- エクトディスプラシンA受容体 (EDAR) 遺伝子のV370A変異は,ヒト集団における陽性選択の有意なマーカーである.
- この変異によって引き起こされる正確な進化のタイミングと特定の現象的結果については,まだ完全に理解されていません.
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