Jove
Visualize
お問い合わせ
JoVE
x logofacebook logolinkedin logoyoutube logo
JoVEについて
概要リーダーシップブログJoVEヘルプセンター
著者向け
出版プロセス編集委員会範囲と方針査読よくある質問投稿
図書館員向け
推薦の声購読アクセスリソース図書館諮問委員会よくある質問
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experimentsアーカイブ
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教員リソースセンター教員サイト
利用規約
プライバシーポリシー
ポリシー

関連する概念動画

Longitudinal Research02:20

Longitudinal Research

11.7K
Sometimes we want to see how people change over time, as in studies of human development and lifespan. When we test the same group of individuals repeatedly over an extended period of time, we are conducting longitudinal research. Longitudinal research is a research design in which data-gathering is administered repeatedly over an extended period of time. For example, we may survey a group of individuals about their dietary habits at age 20, retest them a decade later at age 30, and then again...
11.7K
Whole Body Regeneration01:33

Whole Body Regeneration

3.6K
Regeneration is the process of restoring injured or lost tissues, organs, or body parts. While simpler organisms generally show greater ability to regenerate their whole body, few complex animals show similarly exceptional regeneration. For example, planarian flatworms have a unique regenerative potential making them a popular study organism among biologists to understand the mechanisms of whole body regeneration. Other organisms, such as hydra, also show extreme regeneration potential;...
3.6K
The Effect of Aging on Tissues01:19

The Effect of Aging on Tissues

3.6K
Several body functions deteriorate with age. The external signs of aging are easily identifiable. For example, the skin becomes dry, less elastic, and thins out, forming wrinkles. The skin of the face begins to appear looser due to a decrease in the levels of elastic and collagen fibers in the connective tissue. Additionally, melanin production in the hair follicle decreases with age, resulting in gray hair. Moreover, the senses of sight and hearing decline, so glasses and hearing aids may...
3.6K
Life Tables01:22

Life Tables

674
A life table is a statistical tool that summarizes the mortality and survival patterns of a population, providing detailed insights into the likelihood of survival or death across different age intervals within a cohort. By organizing data on survival probabilities and mortality rates, life tables offer a clear snapshot of population dynamics over time. They are extensively used in demography, public health, actuarial science, and ecology to analyze life expectancy, design health interventions,...
674
Aging01:26

Aging

1.1K
Aging is a complex biological phenomenon influenced by various processes that affect cellular and systemic functions. Several prominent theories attempt to explain its mechanisms, highlighting cellular limitations, oxidative damage, and hormonal changes as central factors in aging.
Cellular Clock Theory
The cellular clock theory posits that the human lifespan is closely tied to the finite capacity of cells to divide, a phenomenon governed by telomeres, which are protective caps at the ends of...
1.1K
Lifestyle Factors and Health01:20

Lifestyle Factors and Health

679
Lifestyle factors play a critical role in maintaining overall health and preventing chronic diseases. Key elements, such as regular physical activity, a nutritious diet, and abstinence from smoking, can significantly enhance physical, mental, and emotional well-being while reducing the risk of several life-threatening conditions.
Benefits of Physical Activity
Physical activity, whether through structured exercise or casual activities like walking, biking, or dancing, is a cornerstone of a...
679

こちらも読む

関連記事

共著者、ジャーナル、引用グラフによってこの研究に関連する記事。

並び替え
Same author

Mitochondria-lysosome coupling contributes to lysosome acidification and aging.

Molecular cell·2026
Same author

Senescent cells secrete chromatin components via senescence-associated extracellular particles.

Research square·2026
Same author

Links Between Autophagy and Healthy Aging.

Journal of molecular biology·2026
Same author

Senescent cells secrete chromatin components via senescence-associated extracellular particles.

bioRxiv : the preprint server for biology·2025
Same author

Interleukin 13 signaling modulates dopaminergic functions and nicotine reward in rodents.

Molecular psychiatry·2025
Same author

Autophagy activator AA-20 improves proteostasis and extends <i>Caenorhabditis elegans</i> lifespan.

Proceedings of the National Academy of Sciences of the United States of America·2025

関連する実験動画

Updated: May 5, 2026

Measuring Caenorhabditis elegans Life Span in 96 Well Microtiter Plates
12:23

Measuring Caenorhabditis elegans Life Span in 96 Well Microtiter Plates

Published on: March 18, 2011

38.4K

長生きするクールな方法

Bruno Conti1, Malene Hansen

  • 1The Scripps Research Institute, Department of Chemical Physiology, La Jolla, CA 92037, USA. bconti@scripps.edu

Cell
|February 19, 2013
PubMed
まとめ

低温は,寒さに敏感なタンパク質であるTRPA-1チャネルを活性化することで寿命を延ばします. この活性化により,神経細胞や他の細胞の信号伝達経路が開始され,Caenorhabditis elegansの長寿を促進します.

科学分野:

  • 分子生物学は分子生物学である.
  • 遺伝学 遺伝学とは
  • 老化に関する研究

背景:

  • 老化における気温の役割は複雑で,以前の理論は熱力学的効果に焦点を当てていた.
  • 温度による長寿の基礎となる分子メカニズムを理解することは,老化に関する研究にとって極めて重要です.

さらに関連する動画

A Simple Method for High Throughput Chemical Screening in Caenorhabditis Elegans
08:49

A Simple Method for High Throughput Chemical Screening in Caenorhabditis Elegans

Published on: March 20, 2018

11.4K
Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

5.5K

関連する実験動画

Last Updated: May 5, 2026

Measuring Caenorhabditis elegans Life Span in 96 Well Microtiter Plates
12:23

Measuring Caenorhabditis elegans Life Span in 96 Well Microtiter Plates

Published on: March 18, 2011

38.4K
A Simple Method for High Throughput Chemical Screening in Caenorhabditis Elegans
08:49

A Simple Method for High Throughput Chemical Screening in Caenorhabditis Elegans

Published on: March 20, 2018

11.4K
Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans
10:08

Surveying Low-Cost Methods to Measure Lifespan and Healthspan in Caenorhabditis elegans

Published on: May 18, 2022

5.5K