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Updated: Feb 2, 2026

Overexpressing Long Noncoding RNAs Using Gene-activating CRISPR
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アクティベーションRNAはメディエーターと結合し,染色体構造と転写を強化する

Fan Lai1, Ulf A Orom, Matteo Cesaroni

  • 1The Wistar Institute, 3601 Spruce Street, Philadelphia, Pennsylvania 19104, USA.

Nature
|February 19, 2013
PubMed
まとめ

長い非コーディングRNA (lncRNA) の活性化により,仲介者複合体が隣接する遺伝子を活性化します. この相互作用は遺伝子調節に極めて重要であり,病気では障害があり,ncrna-a機能におけるメディエーターの役割を強調しています.

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